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Search Results for " protein secretion "

ターゲット

48

阻害剤

6

天然化合物

75

リコンビナントタンパク質

1

ライブラリー

カタログ番号 製品名 別名 ターゲット
T9349 IXA4 IRE1
IXA4 is a highly selective, nontoxic activator of IRE1/XBP1s and reduces APP secretion by activating IRE1. IXA4-stimulated IRE1 activation also enhanced pancreatic function.
T21623 AS1269574 AS 1269574 GPR , TRP/TRPV Channel
AS1269574 is a potent, orally available GPR119 agonist. AS1269574(AS 1269574) has the potential for the research of type 2 diabetes.
T7490 ARN2966 Beta Amyloid
ARN2966 is an inhibitor of amyloid precursor protein (APP)and amyloid-β (Aβ) secretion.
T22922 Lenalidomide hemihydrate TNF , Ligand for E3 Ligase , Molecular Glues
Lenalidomide hemihydrate is a TNF-α secretion inhibitor (IC50 = 13 nM). Lenalidomide hemihydrate could bound endogenous CRBN and recombinant CRBN-DNA damage binding protein-1 (DDB1) complexes.
T61439 DSS30 Beta Amyloid , BACE , CDK
DSS30 is a P25/CDK5 inhibitor.DSS30 acts by inhibiting the phosphorylation of amyloid precursor protein cleaving enzyme 1 (BACEl), which reduces the secretion of β-amyloid (Aβ).DSS30 can be used for the prevention and tr...
T12781 RV01 Others
RV01 is a novel quinoline-substituted analogue of resveratrol that inhibits DNA damage, reduces ethanol-induced acetaldehyde dehydrogenase (ALDH2) mRNA expression, and has hydroxyl radical scavenging activity. rV01 reduc...
T11798 L-692429 MK-0751 GHSR , GPCR19
TP1516L C-Reactive Protein (CRP) 77-82 acetate C-Reactive Protein (CRP) 77-82 acetate(130349-01-8 free base) Others
C-Reactive Protein (CRP) 77-82 acetate is the 77-82 fragment of C-Reactive Protein. C-Reactive Protein (CRP), the prototypic marker of inflammation, is a cardiovascular risk marker and may promote atherogenesis.C-reactiv...
T9857 Vasopressin antidiuretic hormone (ADH),argipressin,arginine vasopressin (AVP) Endogenous Metabolite
Vasopressin (argipressin), a cyclic nine-peptide synthesized by hypothalamic neurons, is one of the hormones involved in peptide prohormone synthesis. Vasopressin is involved in the regulation process of hypothalamic-pit...
TP2158 TRV-120027 TFA TRV-120027 TFA (1234510-46-3 free base) RAAS , Arrestin
TRV120027 TFA is a β-arrestin-1-biased agonist of the angiotensin II receptor type 1 (AT1R) and engages ß-arrestins while blocking G-protein signaling.
T29701 AG 85 AG85,AG-85
AG 85 is a major secretion protein of Mycobacterium tuberculosis.
T40145 Sec61-IN-3 Sec61-IN-3
Sec61-IN-2 (A3) is a protein secretion inhibitor.
T40147 Sec61-IN-2 Sec61-IN-2
Sec61-IN-2 (A347) is a protein secretion inhibitor.
T11846 LHVS Cysteine Protease
LHVS effectively blocks T. gondii microneme protein secretion (IC50=10 μM), gliding motility, and cell invasion. LHVS is a potent, non-selective cysteine protease inhibitor.
T68573 Tigapotide triflutate
Tigapotide triflutate is a synthetic peptide corresponding to amino acids 31-45 of PSP94 (prostate secretory protein) that inhibits matrix metalloproteinase-9 secretion.
T68574 Tigapotide Free Base
Tigapotide Free Base is a synthetic peptide corresponding to amino acids 31-45 of PSP94 (prostate secretory protein) that inhibits matrix metalloproteinase-9 secretion.
TP1241 Adrenocorticotropic Hormone (ACTH) (18-39), human ACTH (18-39), human
Adrenocorticotropic Hormone (ACTH) (18-39) is known as the Corticotropin-like Intermediate Lobe Peptide. It stimulates insulin secretion as well as amylase and protein secretion in a dose-dependent manner similar to thos...
T7005L Ulixertinib hydrochloride Ulixertinib HCl,BVD-523,VRT752271,BVD 523,BVD523,VRT 752271
Ulixertinib is an inhibitor of ERK protein kinase. Downmodulation of ERK protein kinase activity inhibits VEGF secretion by human myeloma cells and myeloma-induced angiogenesis. Upon oral administration, BVD-523 inhibits...
T82990 AP-C4
AP-C4 is a selective inhibitor targeting guanosine 3′,5′-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII), exhibiting a pIC50 value of 5.2. Conversely, AP-C3 does not inhibit cGKII-mediated anion secretion...
T82988 AP-C7
AP-C7 is a selective inhibitor of cGMP-dependent protein kinase II (cGKII) with a pIC50 value of 5.0, demonstrating only weak inhibition of cGKII-dependent anion secretion [1].
TP2056 Acetyl-Calpastatin(184-210)(human) Acetyl-Calpastatin (184-210) (human)
Selective calpain inhibitor. Strongly inhibits calpain I (Ki = 0.2 nM) and II but does not inhibit papain, trypsin and cathepsin L (Ki = 6 μM). Increases secretion of amyoid β-protein (Aβ) 42, Aβ40 and Aβ42 ratio.
T83053 Anti-inflammatory agent 59
Anti-inflammatory agent 58 is characterized by its ability to inhibit IL-1β with an IC50 value of 2.28 μM. Furthermore, it reduces pro-inflammatory gene expression, protein secretion, and NF-κB phosphorylation [1].
T76094 Mastoparan X
Mastoparan X, a tetradecapeptide derived from wasp venom, functions as a GTP-binding regulatory protein (G protein)-activating peptide. It directly activates G proteins coupled to phospholipase C, inducing secretion in v...
T81126 SORT-PGRN interaction inhibitor 2
SORT-PGRN Interaction Inhibitor 2 is a compound that downregulates SORT1 protein expression and enhances extracellular progranulin (PGRN) secretion in various mammalian cell lines, and is utilized in the study of neurolo...
T82992 AP-C1
AP-C1 is a potent inhibitor of cGMP-dependent protein kinase II (cGKII), exhibiting a pIC50 value of 6.5, yet it only weakly inhibits cGKII-dependent anion secretion [1].
T38384 Nexinhib20
Nexinhib20 is an inhibitor of the protein-protein interaction between the small GTPase Rab27a and its effector JFC1 (IC50 = 2.6 μM).[1] It inhibits myeloperoxidase (MPO) secretion induced by granulocyte macrophage colony...
T78930 T3SS-IN-1
T3SS-IN-1 (compound B9) is a potent type III secretion system (T3SS) inhibitor that also suppresses hpa1 promoter activity and harpin protein expression, without impacting bacterial growth [1].
T70468 MK-8666
MK-8666 is a partial GPCR (G-protein-coupled receptor) agonist that is coordinated with the action of GPR40. GPR40, also known as free fatty acid (FFA) receptor 1 modulates fatty acid-induced insulin secretion in pancrea...
T78037 Hepcidin-1 (mouse) TFA
Hepcidin-1 (mouse) TFA, an endogenous peptide hormone, regulates iron homeostasis by upregulating mRNA levels of TRAP, cathepsin K, and MMP-9, enhancing TRAP-5b protein secretion, and downregulating FPN1 protein levels, ...
T69380 Cinnamic acid, hydrazide
Cinnamic acid, hydrazide is an unsaturated carboxylic acid and precursor to aspartame via enzyme-catalysed amination to phenylalanine. Cinnamic acid may be useful in prevention or treatment of Diabetes through various me...
T80108 Hepcidin-1 (mouse)
Hepcidin-1 (mouse) is a peptide hormone that regulates iron balance, elevates mRNA for TRAP, cathepsin K, and MMP-9, and promotes TRAP-5b protein secretion. This compound also reduces FPN1 protein levels and boosts intra...
T82991 AP-C3
AP-C3 is a potent inhibitor of guanosine 3′,5′-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII), exhibiting a pIC50 value of 6.3 and demonstrating only weak inhibition of cGKII-dependent anion secretion [1...
T26868 BMS-986118 BMS 986118
BMS-986118 is a full agonist of GPR40, is a G-protein-coupled receptor expressed primarily in pancreatic islets and intestinal L-cells that has been a target of significant recent therapeutic interest for type II diabete...
T83054 Anti-inflammatory agent 58
Anti-inflammatory agent 58 exhibits IL-1β inhibition with an IC50 value of 1.08 μM and suppresses pro-inflammatory gene expression, protein secretion, and NF-κB phosphorylation [1].
T69953 MK-8666 Tris
MK-8666 Tris is a partial GPCR (G-protein-coupled receptor) agonist that is coordinated with the action of GPR40. GPR40, also known as free fatty acid (FFA) receptor 1 modulates fatty acid-induced insulin secretion in pa...
T63339 ALV1
ALV1 is a potent degradation agent of Ikaros and Helios, with similar degradation activity against IKZF1/2/3. ALV1 significantly reduced the protein abundance of IKZF1-4, CK1α (casein kinase 1α, CSNK1A1) and ribosomal pr...
T35839 3-Iodothyronamine (hydrochloride)
3-Iodothyronamine is derived from the deiodination and decarboxylation of endogenous thyroxine. It activates the G protein-coupled receptor known as trace amine-associated receptor 1 at nanomolar concentrations whereupon...
T37545 Cis-9,10-Methyleneoctadecanoic Acid
cis-9,10-Methyleneoctadecanoic acid is a cyclopropane fatty acid that has been found in bacteria and the digestive gland of P. globosa. It is a component of S. aureus cell membranes and levels decrease upon treatment wit...
T82938 ATUX-1215
ATUX-1215, a protein phosphatase 2A (PP2A) activator, diminishes the phosphorylation of ERK, p38, JNK, and Akt, as well as decreases the secretion of IL-12p70, GM-CSF, and IL1α in BLM-treated animals, potentially deceler...
TP1516 C-Reactive Protein (CRP) (77-82) C-Reactive Protein (CRP) 77-82
C-Reactive Protein (CRP) 77-82 is the 77-82 fragment of C-Reactive Protein. C-Reactive Protein (CRP), the prototypic marker of inflammation, is a cardiovascular risk marker and may promote atherogenesis.C-reactive protei...
T35604 Osteocalcin (1-49) (human) (trifluoroacetate salt)
Osteocalcin (1-49) is a non-collagenous peptide that is secreted by osteoblasts and odontoblasts and comprises 1-2% of the total protein in bone. Secretion of osteocalcin (1-49) is stimulated by 1,25-dihydroxy vitamin D ...
T35794 Kisspeptin-54 (human) (trifluoroacetate salt)
Kisspeptin-54 is a peptide ligand of the orphan G protein-coupled receptor GPR54 (Kis = 1.81 and 1.45 nM for rat and human receptors, respectively).1 It is a 54 amino acid peptide encoded by the metastasis suppressor gen...
T35599 Neuropeptide Y (3-36) (human, rat) (trifluoroacetate salt)
Neuropeptide Y (NPY) (3-36) is a C-terminal fragment of NPY, a neuropeptide involved in controlling appetite, blood pressure, cardiac contractility, and intestinal secretion. NPY (3-36) is an endogenous peptide produced ...
T83827 Adenosine-5'-O-(3-thiotriphosphate) sodium ATPγS,Adenosine 5'-(γ-thio)-triphosphate
Adenosine-5'-O-(3-thiotriphosphate) (ATPγS), an agonist of the purinergic P2Y11 receptor, prompts inositol phosphate accumulation in CHO-K1 cells harboring the human or canine P2Y11 receptor with EC50 values of 1.2 and 1...
T83681 IRBP (1-20) (human, rat) TFA IRBP1-20,Interphotoreceptor Retinoid-Binding Protein (1-20)
Interphotoreceptor retinoid-binding protein (1-20) (IRBP1-20), a dodecapeptide fragment of retinoid-binding protein 3, plays a crucial role in pigment regeneration by facilitating the transport of retinol and retinal bet...
T80653 Larixol (+)-Larixol Akt
Larixol acts as both an fMLP inhibitor and a modulator of various signaling pathways by inhibiting Src kinase, ERK1/2, p38, and AKT phosphorylation critical for immune responses. It disrupts the interaction between the β...
T36629 Givinostat
Givinostat (ITF-2357) is a HDAC inhibitor with an IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively. Givinostat (ITF2357) suppresses total LPS-induced IL-1β production robustly compared with the reduction by ITF30...
T36779 NG 25 (hydrochloride hydrate)
NG 25 is a type II kinase inhibitor that inhibits MAP4K2 and TAK1 (IC50s = 21.7 and 149 nM, respectively).1It also inhibits the Src family kinases Src and LYN (IC50s = 113 and 12.9 nM, respectively) and Abl family kinase...

Compounds

IXA4
T9349
Synonym:
Target: IRE1
AS1269574
T21623
Synonym: AS 1269574
Target: GPR, TRP/TRPV Channel
ARN2966
T7490
Synonym:
Target: Beta Amyloid
Lenalidomide hemihydrate
T22922
Synonym:
Target: TNF, Ligand for E3 Ligase, Molecular Glues
DSS30
T61439
Synonym:
Target: Beta Amyloid, BACE, CDK
RV01
T12781
Synonym:
Target: Others
L-692429
T11798
Synonym: MK-0751
Target: GHSR, GPCR19
C-Reactive Protein (CRP) 77-82 acetate
TP1516L
Synonym: C-Reactive Protein (CRP) 77-82 acetate(130349-01-8 free base)
Target: Others
Vasopressin
T9857
Synonym: antidiuretic hormone (ADH),argipressin,arginine vasopressin (AVP)
Target: Endogenous Metabolite
TRV-120027 TFA
TP2158
Synonym: TRV-120027 TFA (1234510-46-3 free base)
Target: RAAS, Arrestin
AG 85
T29701
Synonym: AG85,AG-85
Target:
Sec61-IN-3
T40145
Synonym: Sec61-IN-3
Target:
Sec61-IN-2
T40147
Synonym: Sec61-IN-2
Target:
LHVS
T11846
Synonym:
Target: Cysteine Protease
Tigapotide triflutate
T68573
Synonym:
Target:
Tigapotide Free Base
T68574
Synonym:
Target:
Adrenocorticotropic Hormone (ACTH) (18-39), human
TP1241
Synonym: ACTH (18-39), human
Target:
Ulixertinib hydrochloride
T7005L
Synonym: Ulixertinib HCl,BVD-523,VRT752271,BVD 523,BVD523,VRT 752271
Target:
AP-C4
T82990
Synonym:
Target:
AP-C7
T82988
Synonym:
Target:
Acetyl-Calpastatin(184-210)(human)
TP2056
Synonym: Acetyl-Calpastatin (184-210) (human)
Target:
Anti-inflammatory agent 59
T83053
Synonym:
Target:
Mastoparan X
T76094
Synonym:
Target:
SORT-PGRN interaction inhibitor 2
T81126
Synonym:
Target:
AP-C1
T82992
Synonym:
Target:
Nexinhib20
T38384
Synonym:
Target:
T3SS-IN-1
T78930
Synonym:
Target:
MK-8666
T70468
Synonym:
Target:
Hepcidin-1 (mouse) TFA
T78037
Synonym:
Target:
Cinnamic acid, hydrazide
T69380
Synonym:
Target:
Hepcidin-1 (mouse)
T80108
Synonym:
Target:
AP-C3
T82991
Synonym:
Target:
BMS-986118
T26868
Synonym: BMS 986118
Target:
Anti-inflammatory agent 58
T83054
Synonym:
Target:
MK-8666 Tris
T69953
Synonym:
Target:
ALV1
T63339
Synonym:
Target:
3-Iodothyronamine (hydrochloride)
T35839
Synonym:
Target:
cis-9,10-Methyleneoctadecanoic Acid
T37545
Synonym:
Target:
ATUX-1215
T82938
Synonym:
Target:
C-Reactive Protein (CRP) (77-82)
TP1516
Synonym: C-Reactive Protein (CRP) 77-82
Target:
Osteocalcin (1-49) (human) (trifluoroacetate salt)
T35604
Synonym:
Target:
Kisspeptin-54 (human) (trifluoroacetate salt)
T35794
Synonym:
Target:
Neuropeptide Y (3-36) (human, rat) (trifluoroacetate salt)
T35599
Synonym:
Target:
Adenosine-5'-O-(3-thiotriphosphate) sodium
T83827
Synonym: ATPγS,Adenosine 5'-(γ-thio)-triphosphate
Target:
IRBP (1-20) (human, rat) TFA
T83681
Synonym: IRBP1-20,Interphotoreceptor Retinoid-Binding Protein (1-20)
Target:
Larixol
T80653
Synonym: (+)-Larixol
Target: Akt
Givinostat
T36629
Synonym:
Target:
NG 25 (hydrochloride hydrate)
T36779
Synonym:
Target:
カタログ番号 製品名 別名 ターゲット
TN1877 Lonicerin Apoptosis , Antibacterial
Lonicerin has antioxidant, anti-arthritic and antifungal activities, it can result in a combination therapy for the treatment of fungal arthritis due to C. albicans infection.
T19117 3-Deoxyglucosone 3-Deoxy-D-glucosone,2-keto-3-Deoxyglucose GPX , Glucagon Receptor
3-Deoxyglucosone(3-Deoxy-D-glucosone) is synthesized by the intermediate pathway of the melad and polyol reactions.3-Deoxyglucosone reacts rapidly with protein amino groups to form advanced glycosylated end proteins (AGE...
T4S0498 Glaucocalyxin A Wangzaozin B,Leukamenin F Apoptosis , Akt , Caspase , PI3K
1. Glaucocalyxin A (Leukamenin F)-SBE-β-CD could be useful with a better solubility and sustained function in drug delivery. 2. Glaucocalyxin A activates caspase-3, decreases BAD phosphorylation, and reduces the expressi...
T4S0878 Prunetin Prunusetin ERK , Dehydrogenase , NF-κB
1. Prunetin (Prunusetin) significantly reduces serum levels of inflammatory cytokines and mortality in mice challenged with lipopolysaccharide. 2. Prunetin mediates anti-obesity/adipogenesis effects by suppressing obesit...
T16011 Manumycin A Prostaglandin Receptor
Manumycin A is an antibiotic. Manumycin A induces apoptosis and exerts antitumor activity. Manumycin A inhibits exosome biogenesis and secretion via targeted inhibition of Ras/Raf/ERK1/2 signaling. Manumycin A acts as a ...
TN1862 Licoflavonol Antifection
Licoflavonol is a novel natural inhibitor of Salmonella T3SS, could be a promising candidate for novel type of anti-virulence drugs, it exhibits a strong inhibitory effect on the secretion of the SPI-1 effector proteins ...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPH-00319 Type III secretion system needle Protein, Burkholderia thailandensis, Recombinant (His) Burkholderia thailandensis P. pastoris (Yeast)
Type III secretion system needle Protein, Burkholderia thailandensis, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 11.9 kDa and the accession number is Q2T727.
TMPJ-01471 Activin A Protein, Human, Mouse, Rat, Cynomolgus, Rhesus, Recombinant Human/Mouse/Rat HEK293 Cells
Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. Activins, members of the TGF-beta superfamily, are disulfide-linked dimeric proteins originally purifi...
TMPH-03354 Progonadoliberin-1/GNRH1 Protein, Rat, Recombinant (His) Rat E. coli
Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones. Progonadoliberin-1/GNRH1 Protein, Rat, Recombinant (His) is expressed in E. coli expression sy...
TMPH-02581 Chymase 1 Protein, Mouse, Recombinant (His) Mouse E. coli
Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion. Chymase 1 Protein, Mouse, Recombinant (His) is expressed i...
TMPH-02716 HADH Protein, Mouse, Recombinant (His & SUMO) Mouse E. coli
Mitochondrial fatty acid beta-oxidation enzyme that catalyzes the third step of the beta-oxidation cycle for medium and short-chain 3-hydroxy fatty acyl-CoAs (C4 to C10). Plays a role in the control of insulin secretion ...
TMPH-03328 Mcpt1 Protein, Rat, Recombinant (Myc) Rat E. coli
Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion. May participate in generating perivascular beta-protein wh...
TMPH-01852 Peptide YY/PYY Protein, Human, Recombinant (GST) Human E. coli
This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility. Peptide YY/PYY Protein, Human, Recombinant (GST) is expressed in E. coli expression syste...
TMPH-01385 GLP1R Protein, Human, Recombinant (His) Human HEK293 Cells
G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a ...
TMPH-01094 CELA2A Protein, Human, Recombinant (His) Human P. pastoris (Yeast)
Elastase that enhances insulin signaling and might have a physiologic role in cellular glucose metabolism. Circulates in plasma and reduces platelet hyperactivation, triggers both insulin secretion and degradation, and i...
TMPH-02582 CELA2A Protein, Mouse, Recombinant (His) Mouse E. coli
Elastase that enhances insulin signaling and might have a physiologic role in cellular glucose metabolism. Circulates in plasma and reduces platelet hyperactivation, triggers both insulin secretion and degradation, and i...
TMPY-01960 Munc18c/STXBP3 Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
Syntaxin-binding protein 3, also known as Platelet Sec1 protein, Protein unc-18 homolog 3, Protein unc-18 homolog C, Unc-18C, Unc18-3 and STXBP3, is a cytoplasm protein which belongs to the STXBP/unc-18/SEC1 family. STXB...
TMPH-02937 TLR11 Protein, Mouse, Recombinant (His & Myc) Mouse E. coli
Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. TLR11 Protein, Mouse, Recombinant (His & Myc) ...
TMPH-03301 GLP1R Protein, Rat, Recombinant (E. coli, His) Rat E. coli
G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a ...
TMPH-02676 GLP1R Protein, Mouse, Recombinant (His & SUMO) Mouse E. coli
G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a ...
TMPK-01152 CHRDL1 Protein, Human, Recombinant (His) Human E. coli
CHRDL1 (Chordin-like 1) is a secreted protein that acts as an antagonist of bone morphogenetic protein (BMP). BMP plays a role as an activator of BMP receptor II (BMPR II), which mediates extracellular to intracellular s...
TMPH-01384 GLP1R Protein, Human, Recombinant (E. coli, His) Human E. coli
G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a ...
TMPH-03294 FGF-23 Protein, Rat, Recombinant (His) Rat P. pastoris (Yeast)
Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Regulator of vitamin-D metabolism. Negatively regulates osteoblasts differentiation and matrix mineralization. Ac...
TMPH-01093 CELA2A Protein, Human, Recombinant (E. coli, His) Human E. coli
Elastase that enhances insulin signaling and might have a physiologic role in cellular glucose metabolism. Circulates in plasma and reduces platelet hyperactivation, triggers both insulin secretion and degradation, and i...
TMPH-00304 SV2A Protein, Bovine, Recombinant (His & Myc) Bovine HEK293 Cells
Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of s...
TMPY-02640 FAM3B Protein, Human, Recombinant (hFc) Human HEK293 Cells
Pancreatic derived factor, also known as FAM3B, is an islet-specific secreted cytokine specifically expressed at high levels in the islets of Langerhans of the endocrine pancreas. FAM3B protein is present in alpha- and b...
TMPH-00317 BipD Protein, Burkholderia pseudomallei, Recombinant (His & Myc) Burkholderia pseudomallei E. coli
Required for invasion of epithelial cells, as well as for survival within host cells, escape from endocytic vesicles and subsequent actin-tail formation. Probably regulates the secretion of effectors BipB and BipC and th...
TMPY-04388 BLK Protein, Human, Recombinant (GST) Human Baculovirus Insect Cells
Tyrosine-protein kinase Blk, also known as B lymphocyte kinase, p55-Blk and BLK, is a member of theprotein kinase superfamily, Tyr protein kinase family and SRC subfamily. BLK / p55-Blk is expressed in lymphatic organ...
TMPK-00192 B7-H2/ICOSLG Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
B7-H2, also known as B7-related protein (B7RP1), ICOS Ligand, and CD275, is an approximately 60 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. B7-H2 is a ligand for the T-cell-specific ce...
TMPK-01264 B7-H2/ICOSLG Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
B7-H2, also known as B7-related protein (B7RP1), ICOS Ligand, and CD275, is an approximately 60 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. B7-H2 is a ligand for the T-cell-specific ce...
TMPH-02078 Semenogelin-1/SEMG1 Protein, Human, Recombinant (His & SUMO) Human E. coli
Predominant protein in semen. It participates in the formation of a gel matrix entrapping the accessory gland secretions and ejaculated spermatozoa. Fragments of semenogelin and/or fragments of the related proteins may c...
TMPJ-00482 SEMG1 Protein, Human, Recombinant (His) Human HEK293 Cells
Semenogelin-1 (SEMG1) is the predominant protein in semen; it is a secretory protein involved in the formation of a gel matrix entrapping the accessory gland secretions and ejaculated spermatozoa. The prostate-specific a...
TMPK-00036 GIP Protein, Human, Recombinant (His) Human HEK293 Cells
The potential application of glucose-dependent insulinotropic polypeptide (gastric inhibitory polypeptide, GIP) in the management of obesity and type 2 diabetes has been controversial. Initial interest in the therapeutic...
TMPH-03550 EsxA Protein, S. aureus, Recombinant (His & SUMO) Staphylococcus aureus E. coli
Virulence factor that is important for the establishment of infection in the host. EsxA is required for EsxB synthesis as well as secretion. Modulates host cell apoptotic pathways and mediates together with EsxB the rele...
TMPK-00890 GIP Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
The potential application of glucose-dependent insulinotropic polypeptide (gastric inhibitory polypeptide, GIP) in the management of obesity and type 2 diabetes has been controversial. Initial interest in the therapeutic...
TMPJ-00081 CNTF Protein, Human, Recombinant Human E. coli
Ciliary Neurotrophic Factor (CNTF) is a potent survival factor for neurons and oligodendrocytes. CNTF has also been shown to prevent the degeneration of motor axons after axotomy. CNTF is highly conserved across species ...
TMPK-00193 B7-H2/ICOSLG Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
B7-H2, also known as B7-related protein (B7RP1), ICOS Ligand, and CD275, is an approximately 60 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. B7-H2 is a ligand for the T-cell-specific ce...
TMPY-01117 MRAP Protein, Human, Recombinant (hFc) Human HEK293 Cells
MRAP (Melanocortin 2 Receptor Accessory Protein) is a Protein Coding gene. This gene encodes a melanocortin receptor-interacting protein. It belongs to the MRAP family. MRAP, which contains a single transmembrane domain,...
TMPH-00864 RO60 Protein, Human, Recombinant (His) Human E. coli
RNA-binding protein that binds to misfolded non-coding RNAs, pre-5S rRNA, and several small cytoplasmic RNA molecules known as Y RNAs. May stabilize some of these RNAs and protect them from degradation. Binds to endogeno...
TMPK-00455 IGF1R/CD221 Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis protection. IGF signalling also influences hypoxia signalling, prot...
TMPK-00768 ANXA1 Protein, Human, Recombinant (His) Human E. coli
Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activ...
TMPH-02522 GHRL Protein, Mouse, Recombinant (His) Mouse E. coli
Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid se...
TMPK-00891 GIP Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
The potential application of glucose-dependent insulinotropic polypeptide (gastric inhibitory polypeptide, GIP) in the management of obesity and type 2 diabetes has been controversial. Initial interest in the therapeutic...
TMPJ-01363 CLIC5 Protein, Human, Recombinant (His) Human E. coli
Chloride Intracellular Channel Protein 5 (CLIC5) is a single-pass membrane protein which belongs to the chloride channel CLIC family. It contains one GST C-terminal domain. Chloride intracellular channels are involved in...
TMPH-03385 Thyroglobulin Protein, Rat, Recombinant (His & SUMO) Rat E. coli
Acts as a substrate for the production of iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). The synthesis of T3 and T4 involves iodination of selected tyrosine residues of TG/thyroglobulin followed by ...
TMPK-01291 ANXA1 Protein, Cynomolgus, Recombinant (His) Cynomolgus E. coli
Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activ...
TMPK-00658 IGF1R/CD221 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis protection. IGF signalling also influences hypoxia signalling, prot...
TMPY-02549 GBP1 Protein, Human, Recombinant (His) Human HEK293 Cells
Guanylate-binding protein 1 (GBP-1) is a member of the GBP family whose members are GTPases induced in response to interferon-λ (IFN-λ), with seven highly homologous members in humans, termed HuGBP-1 to HuGBP-7. GBP-1 ex...
TMPH-01391 GPI Protein, Human, Recombinant (His) Human E. coli
In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis. Besides it's role as a glycolytic enzyme, also ac...
TMPH-01729 Myosin-9/MYH9 Protein, Human, Recombinant (GST) Human E. coli
Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Required for cortical actin clearance prior to oocyte exocytosis. Promotes cell motility in...
TMPH-02678 GPI Protein, Mouse, Recombinant (His) Mouse P. pastoris (Yeast)
In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis. Besides it's role as a glycolytic enzyme, also ac...
TMPK-01020 FSHB Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
Fertility is dependent on follicle-stimulating hormone (FSH), a product of gonadotrope cells of the anterior pituitary gland. Hypothalamic gonadotropin-releasing hormone (GnRH) and intra-pituitary activins are regarded a...
TMPK-00799 ANXA1 Protein, Mouse, Recombinant (His) Mouse E. coli
Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activ...
TMPK-01285 FSHB Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
Fertility is dependent on follicle-stimulating hormone (FSH), a product of gonadotrope cells of the anterior pituitary gland. Hypothalamic gonadotropin-releasing hormone (GnRH) and intra-pituitary activins are regarded a...
TMPK-00456 IGF1R/CD221 Protein, Human, Recombinant (aa 31-932, His & Avi), Biotinylated Human HEK293 Cells
The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis protection. IGF signalling also influences hypoxia signalling, prot...
TMPH-01559 IL-26 Protein, Human, Recombinant (His) Human P. pastoris (Yeast)
May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expre...
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Type III secretion system needle Protein, Burkholderia thailandensis, Recombinant (His)
TMPH-00319
Species: Burkholderia thailandensis
Expression System: P. pastoris (Yeast)
Activin A Protein, Human, Mouse, Rat, Cynomolgus, Rhesus, Recombinant
TMPJ-01471
Species: Human/Mouse/Rat
Expression System: HEK293 Cells
Progonadoliberin-1/GNRH1 Protein, Rat, Recombinant (His)
TMPH-03354
Species: Rat
Expression System: E. coli
Chymase 1 Protein, Mouse, Recombinant (His)
TMPH-02581
Species: Mouse
Expression System: E. coli
HADH Protein, Mouse, Recombinant (His & SUMO)
TMPH-02716
Species: Mouse
Expression System: E. coli
Mcpt1 Protein, Rat, Recombinant (Myc)
TMPH-03328
Species: Rat
Expression System: E. coli
Peptide YY/PYY Protein, Human, Recombinant (GST)
TMPH-01852
Species: Human
Expression System: E. coli
GLP1R Protein, Human, Recombinant (His)
TMPH-01385
Species: Human
Expression System: HEK293 Cells
CELA2A Protein, Human, Recombinant (His)
TMPH-01094
Species: Human
Expression System: P. pastoris (Yeast)
CELA2A Protein, Mouse, Recombinant (His)
TMPH-02582
Species: Mouse
Expression System: E. coli
Munc18c/STXBP3 Protein, Human, Recombinant (His & GST)
TMPY-01960
Species: Human
Expression System: Baculovirus Insect Cells
TLR11 Protein, Mouse, Recombinant (His & Myc)
TMPH-02937
Species: Mouse
Expression System: E. coli
GLP1R Protein, Rat, Recombinant (E. coli, His)
TMPH-03301
Species: Rat
Expression System: E. coli
GLP1R Protein, Mouse, Recombinant (His & SUMO)
TMPH-02676
Species: Mouse
Expression System: E. coli
CHRDL1 Protein, Human, Recombinant (His)
TMPK-01152
Species: Human
Expression System: E. coli
GLP1R Protein, Human, Recombinant (E. coli, His)
TMPH-01384
Species: Human
Expression System: E. coli
FGF-23 Protein, Rat, Recombinant (His)
TMPH-03294
Species: Rat
Expression System: P. pastoris (Yeast)
CELA2A Protein, Human, Recombinant (E. coli, His)
TMPH-01093
Species: Human
Expression System: E. coli
SV2A Protein, Bovine, Recombinant (His & Myc)
TMPH-00304
Species: Bovine
Expression System: HEK293 Cells
FAM3B Protein, Human, Recombinant (hFc)
TMPY-02640
Species: Human
Expression System: HEK293 Cells
BipD Protein, Burkholderia pseudomallei, Recombinant (His & Myc)
TMPH-00317
Species: Burkholderia pseudomallei
Expression System: E. coli
BLK Protein, Human, Recombinant (GST)
TMPY-04388
Species: Human
Expression System: Baculovirus Insect Cells
B7-H2/ICOSLG Protein, Human, Recombinant (His & Avi)
TMPK-00192
Species: Human
Expression System: HEK293 Cells
B7-H2/ICOSLG Protein, Cynomolgus, Recombinant (His)
TMPK-01264
Species: Cynomolgus
Expression System: HEK293 Cells
Semenogelin-1/SEMG1 Protein, Human, Recombinant (His & SUMO)
TMPH-02078
Species: Human
Expression System: E. coli
SEMG1 Protein, Human, Recombinant (His)
TMPJ-00482
Species: Human
Expression System: HEK293 Cells
GIP Protein, Human, Recombinant (His)
TMPK-00036
Species: Human
Expression System: HEK293 Cells
EsxA Protein, S. aureus, Recombinant (His & SUMO)
TMPH-03550
Species: Staphylococcus aureus
Expression System: E. coli
GIP Protein, Mouse, Recombinant (hFc)
TMPK-00890
Species: Mouse
Expression System: HEK293 Cells
CNTF Protein, Human, Recombinant
TMPJ-00081
Species: Human
Expression System: E. coli
B7-H2/ICOSLG Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00193
Species: Human
Expression System: HEK293 Cells
MRAP Protein, Human, Recombinant (hFc)
TMPY-01117
Species: Human
Expression System: HEK293 Cells
RO60 Protein, Human, Recombinant (His)
TMPH-00864
Species: Human
Expression System: E. coli
IGF1R/CD221 Protein, Human, Recombinant (His & Avi)
TMPK-00455
Species: Human
Expression System: HEK293 Cells
ANXA1 Protein, Human, Recombinant (His)
TMPK-00768
Species: Human
Expression System: E. coli
GHRL Protein, Mouse, Recombinant (His)
TMPH-02522
Species: Mouse
Expression System: E. coli
GIP Protein, Mouse, Recombinant (His)
TMPK-00891
Species: Mouse
Expression System: HEK293 Cells
CLIC5 Protein, Human, Recombinant (His)
TMPJ-01363
Species: Human
Expression System: E. coli
Thyroglobulin Protein, Rat, Recombinant (His & SUMO)
TMPH-03385
Species: Rat
Expression System: E. coli
ANXA1 Protein, Cynomolgus, Recombinant (His)
TMPK-01291
Species: Cynomolgus
Expression System: E. coli
IGF1R/CD221 Protein, Cynomolgus, Recombinant (His)
TMPK-00658
Species: Cynomolgus
Expression System: HEK293 Cells
GBP1 Protein, Human, Recombinant (His)
TMPY-02549
Species: Human
Expression System: HEK293 Cells
GPI Protein, Human, Recombinant (His)
TMPH-01391
Species: Human
Expression System: E. coli
Myosin-9/MYH9 Protein, Human, Recombinant (GST)
TMPH-01729
Species: Human
Expression System: E. coli
GPI Protein, Mouse, Recombinant (His)
TMPH-02678
Species: Mouse
Expression System: P. pastoris (Yeast)
FSHB Protein, Mouse, Recombinant (hFc)
TMPK-01020
Species: Mouse
Expression System: HEK293 Cells
ANXA1 Protein, Mouse, Recombinant (His)
TMPK-00799
Species: Mouse
Expression System: E. coli
FSHB Protein, Cynomolgus, Recombinant (His)
TMPK-01285
Species: Cynomolgus
Expression System: HEK293 Cells
IGF1R/CD221 Protein, Human, Recombinant (aa 31-932, His & Avi), Biotinylated
TMPK-00456
Species: Human
Expression System: HEK293 Cells
IL-26 Protein, Human, Recombinant (His)
TMPH-01559
Species: Human
Expression System: P. pastoris (Yeast)
カタログ番号 製品名
L9700 Endoplasmic Reticulum Stress Compound Library

193 compounds
A unique collection of 193 endoplasmic reticulum stress (ER stress) related compounds used for high throughput screening (HTS) and high content screening (HCS);